Neutrophil Reverse Migration and a Chemokinetic Resolution

Laurel E Hind; Anna Huttenlocher

doi:10.1016/j.devcel.2018.11.004

Neutrophil Reverse Migration and a Chemokinetic Resolution

Dev Cell. 2018 Nov 19;47(4):404-405. doi: 10.1016/j.devcel.2018.11.004.

Authors

Laurel E Hind¹, Anna Huttenlocher²

Affiliations

¹ Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.
² Department of Medical Microbiology and Immunology and Pediatrics, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: huttenlocher@wisc.edu.

PMID: 30458135
DOI: 10.1016/j.devcel.2018.11.004

Abstract

Neutrophil migration to sites of injury or infection is a critical first step in innate immunity. Resolution of neutrophil inflammation is essential for tissue repair but is less well understood. Recent work using intravital imaging in mice to visualize neutrophil dynamics at sterile injuries has advanced our understanding of neutrophil reverse migration and resolution of inflammation in mammals.

Publication types

Comment

MeSH terms

Animals
Cell Movement*
Immunity, Innate
Inflammation
Mice
Neutrophils*

Grants and funding

T32 HL007899/HL/NHLBI NIH HHS/United States