Anatomic Localization of Type 1 and Type 2 Macular Neovascularization Using Swept-Source OCT Angiography

Ophthalmic Surg Lasers Imaging Retina. 2018 Nov 1;49(11):878-886. doi: 10.3928/23258160-20181101-09.

Abstract

Background and objective: Swept-source optical coherence tomography angiography (SS-OCTA) and different boundary-specific segmentation strategies were used to distinguish type 1 macular neovascularization (MNV) from type 2 MNV in eyes with exudative age-related macular degeneration (AMD).

Patients and methods: Eyes with exudative AMD were enrolled in a prospective study. Segmentation strategies included a slab from the outer retina (OR) to the choriocapillaris (CC) for the entire MNV, a slab from the retinal pigment epithelium (RPE) to the CC for the type 1 MNV, and a slab from the OR to the RPE for the type 2 MNV.

Results: In 13 eyes, SS-OCTA B-scans and en face images using different segmentation strategies were able to identify type 1 and type 2 components of the MNV.

Conclusion: In eyes with exudative AMD, SS-OCTA imaging and commercially available boundary-specific segmentation strategies were used to distinguish between type 1 and type 2 MNV. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:878-886.].

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Diagnosis, Differential
  • Female
  • Fluorescein Angiography / methods*
  • Fundus Oculi
  • Humans
  • Macula Lutea / blood supply
  • Macula Lutea / pathology*
  • Male
  • Prospective Studies
  • Retinal Neovascularization / diagnosis*
  • Tomography, Optical Coherence / methods*
  • Wet Macular Degeneration / diagnosis*