Factors limiting physical activity after acute type A aortic dissection

Wien Klin Wochenschr. 2019 Apr;131(7-8):174-179. doi: 10.1007/s00508-018-1412-2. Epub 2018 Nov 19.

Abstract

Background: Acute type A aortic dissection (AAD) leads to high hospital mortality rates in the first 48 h after the onset of symptoms. Survivors, however, have good long-term perspectives and enhanced survival especially if regaining moderate amounts of physical activity.

Methods: This study analyzed 131 survivors (from 180 consecutive patients, aged 60 years (rande 30-84 years, 71% male) of acute AAD after a median time of 44 months (range 1-147 months). The hospital mortality was 13.5%. The group of physically active patients was compared with those with a sedentary life style. The qualitative and quantitative data on physical activity were correlated with data from an aortic registry.

Results: Overall 87% of patients reported 1 or more types of physical activities after hospital discharge. The most common types were walking (51%), biking (29%), hiking (15%) and gymnastics (14%). Patients with a sedentary life style underwent longer hypothermic circulatory arrest times (39 min, range 8-167 min vs. 47 min, range 27-79 min, p = 0.009), had a longer intensive care unit (ICU) stay (Pearsons r = -0.226 [between length of ICU stay and hours of physical activity after hospital discharge], p = 0.033) and suffered more frequently from postoperative paresis (33.3% vs. 3.8%, p < 0.001) compared with physically active patients. Binary logistic regression analysis showed female gender (p = 0.026) and higher body mass index (p = 0.019) to be independently associated with a reduced amount of physical activity.

Conclusions: This study demonstrate that the majority of survivors of acute aortic dissection type A regain a physically active life including the practice of a variety of sports. Factors predictive of a sedentary life style can be identified. Female patients deserve special attention.

Keywords: Aortic dissection type A; Ascending aorta; Physical activity; Sedentary behavior; Sports.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aortic Aneurysm
  • Aortic Dissection* / mortality
  • Exercise / physiology*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Survival Analysis
  • Treatment Outcome