Immunoglobulin A Nephropathy and Immunoglobulin A Vasculitis

Pediatr Clin North Am. 2019 Feb;66(1):101-110. doi: 10.1016/j.pcl.2018.08.008.

Abstract

Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are common glomerulopathies in the pediatric population that deserve special attention. In some cases the primary care provider can follow the patient but others need more intensive management. Delaying this treatment can lead to worse morbidity. This article provides information on the pathogenesis, outcomes, and follow-up strategies that will aid in the diagnosis and referral of patients at risk for kidney disease.

Keywords: Henoch- Schönlein purpura nephritis (HSPN); Immunoglobulin A (IgA) nephropathy (IgAN); Immunoglobulin A vasculitis (IgAV) or anaphylactoid purpura nephropathy.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use*
  • Child
  • Diagnosis, Differential
  • Fish Oils / therapeutic use*
  • Glomerulonephritis, IGA / diagnosis*
  • Glomerulonephritis, IGA / drug therapy*
  • Glomerulonephritis, IGA / immunology
  • Humans
  • IgA Vasculitis / diagnosis*
  • IgA Vasculitis / drug therapy*
  • IgA Vasculitis / immunology
  • Immunosuppressive Agents / therapeutic use*

Substances

  • Adrenal Cortex Hormones
  • Fish Oils
  • Immunosuppressive Agents