Antibacterial and antifungal properties of crude extracts and isolated compounds from Lychnophora markgravii

Nat Prod Res. 2020 Mar;34(6):863-867. doi: 10.1080/14786419.2018.1503263. Epub 2018 Nov 16.

Abstract

Antimicrobial activity of dichloromethane and ethanol extracts and five compounds: pinostrobin (I), pinocembrin (II), tectochrysin (III), galangin 3-methyl ether (IV) and tiliroside (V) isolated from Lychnophora markgravii aerial parts against fifteen microorganisms was determined. The structures of these compounds were elucidated based on ESI-MS and NMR spectroscopic data. Both extracts showed antimicrobial activity against several tested microorganisms. Pinostrobin, tectochrysin and galangin 3-methyl ether showed the strongest antibacterial and antifungal effects.

Keywords: Lychnophora markgravii; antimicrobial activity; flavonoids; plant extract.

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification*
  • Antifungal Agents / pharmacology
  • Asteraceae / chemistry*
  • Flavanones / analysis
  • Flavanones / chemistry
  • Flavonoids / analysis
  • Flavonoids / chemistry
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Plant Extracts / chemistry*

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Flavanones
  • Flavonoids
  • Plant Extracts
  • galangin
  • tiliroside
  • pinocembrin
  • tectochrysin
  • pinostrobin