Uncommon lymphoplasmacytic lymphoma with IgA paraproteinemia: a challenging clinical diagnosis solved by MYD88 mutation analysis

Ann Hematol. 2019 Jun;98(6):1507-1508. doi: 10.1007/s00277-018-3545-9. Epub 2018 Nov 13.

Authors

Giovanni Martino¹, Andrea Marra¹, Stefano Ascani², Paolo Sportoletti³

Affiliations

¹ Hematology and Clinical Immunology, University of Perugia, Perugia, Italy.
² Department of Experimental Medicine-Section of Pathologic Anatomy and Histology Medical School, University of Perugia, Perugia, Italy.
³ Hematology and Clinical Immunology, University of Perugia, Perugia, Italy. paolo.sportoletti@unipg.it.

PMID: 30426157
DOI: 10.1007/s00277-018-3545-9

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Aged
B-Lymphocytes / immunology
B-Lymphocytes / pathology
Bone Marrow / pathology
DNA Mutational Analysis
Humans
Immunoglobulin A / analysis*
Immunoglobulin kappa-Chains / analysis
Male
Mutation, Missense*
Myeloid Differentiation Factor 88 / genetics*
Paraproteins / analysis*
Plasma Cells / immunology
Plasma Cells / pathology
Point Mutation*
Waldenstrom Macroglobulinemia / complications
Waldenstrom Macroglobulinemia / diagnosis*
Waldenstrom Macroglobulinemia / genetics
Waldenstrom Macroglobulinemia / immunology

Substances

Immunoglobulin A
Immunoglobulin kappa-Chains
MYD88 protein, human
Myeloid Differentiation Factor 88
Paraproteins

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