Anti-aging effects of ingenol mebutate for patients with actinic keratosis

J Am Acad Dermatol. 2018 Dec;79(6):1148-1150. doi: 10.1016/j.jaad.2018.05.1244.

Authors

Miri Kim¹, Yujin Jung¹, Jongsic Kim¹, Seo-Won Jeong¹, Yu Ri Woo¹, Hyun Jeong Park²

Affiliations

¹ Department of Dermatology, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea.
² Department of Dermatology, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea. Electronic address: hjpark@catholic.ac.kr.

PMID: 30420007
DOI: 10.1016/j.jaad.2018.05.1244

No abstract available

MeSH terms

Administration, Cutaneous
Aged
Aged, 80 and over
Collagen Type I / biosynthesis
Collagen Type I / genetics
Diterpenes / therapeutic use*
Female
Gels
Humans
Keratosis, Actinic / drug therapy*
Male
Matrix Metalloproteinase 1 / biosynthesis
Matrix Metalloproteinase 1 / genetics
Middle Aged
RNA, Messenger / biosynthesis
Rejuvenation*
Skin / drug effects
Skin / metabolism
Skin Aging / drug effects*
Transforming Growth Factor beta / biosynthesis
Transforming Growth Factor beta / genetics
Treatment Outcome

Substances

3-ingenyl angelate
Collagen Type I
Diterpenes
Gels
RNA, Messenger
Transforming Growth Factor beta
MMP1 protein, human
Matrix Metalloproteinase 1