Military-related risk factors for dementia

Alzheimers Dement. 2018 Dec;14(12):1651-1662. doi: 10.1016/j.jalz.2018.08.011. Epub 2018 Nov 8.

Abstract

Introduction: In recent years, there has been growing discussion to better understand the pathophysiological mechanisms of traumatic brain injury and post-traumatic stress disorder and how they may be linked to an increased risk of neurodegenerative diseases including Alzheimer's disease in veterans.

Methods: Building on that discussion, and subsequent to a special issue of Alzheimer's & Dementia published in June 2014, which focused on military risk factors, the Alzheimer's Association convened a continued discussion of the scientific community on December 1, 2016.

Results: During this meeting, participants presented and evaluated progress made since 2012 and identified outstanding knowledge gaps regarding factors that may impact veterans' risk for later life dementia.

Discussion: The following is a summary of the invited presentations and moderated discussions of both the review of scientific understanding and identification of gaps to inform further investigations.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Brain Injuries, Traumatic / complications
  • Brain Injuries, Traumatic / epidemiology
  • Brain Injuries, Traumatic / genetics
  • Brain Injuries, Traumatic / physiopathology
  • Congresses as Topic
  • Dementia / epidemiology
  • Dementia / etiology*
  • Dementia / genetics
  • Dementia / physiopathology
  • Humans
  • Military Personnel*
  • Risk Factors
  • Veterans*