Rosuvastatin pharmacogenetics in African populations

Pharmacogenomics. 2018 Dec;19(18):1373-1375. doi: 10.2217/pgs-2018-0168. Epub 2018 Nov 6.

Authors

Nyarai Desiree Soko¹, Collen Masimirembwa², Collet Dandara³

Affiliations

¹ Department of Biochemistry, Faculty of Science, University of Zimbabwe, Harare, Zimbabwe.
² African Institute of Biomedical Science & Technology (AiBST), DMPK Department, Wilkins Hospital, Corner Rekai Tangwena & Josiah Tongogara Avenue, Harare, Zimbabwe.
³ Department of Pathology, Division of Human Genetic, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

PMID: 30398065
DOI: 10.2217/pgs-2018-0168

No abstract available

Keywords: 3-hydroxymethylglutaryl co-enzyme A reductase; ABCG2; African populations; LDL; SLCO1B1; cholesterol; rosuvastatin.

Publication types

Editorial

MeSH terms

Africa
Black People / genetics*
Hepatocytes / metabolism
Humans
Pharmacogenetics / methods
Polymorphism, Single Nucleotide / genetics
Rosuvastatin Calcium / pharmacokinetics*

Substances

Rosuvastatin Calcium