New Metrics in High-Resolution and High-Definition Anorectal Manometry

Curr Gastroenterol Rep. 2018 Nov 5;20(12):57. doi: 10.1007/s11894-018-0662-5.

Abstract

Purpose of review: To review recently published diagnostic methods that use high-resolution (HR-) or high-definition- (HD-) anorectal manometry (ARM) techniques.

Recent findings: The integrated pressurized volume (IPV) is a new measure based on spatiotemporal plots obtained from HR-ARM. The IPV may be clinically useful for improving the prediction of abnormal balloon expulsion test in patients with constipation and for discriminating patients with anorectal disorders from asymptomatic controls. Combination of IPV parameters was superior to conventional manometric parameters in predicting the responsiveness to biofeedback therapy. Moreover, several novel parameters including the HR-ARM resting integral, HR-ARM squeeze profile, and anorectal asymmetry index may each be useful as predictive factors for identifying patients with fecal incontinence. HR- and HD-ARM are increasingly performed worldwide for evaluation of anorectal function. Here, we describe new metrics whose clinical significance has not been fully established. Further standardization and validation of these metrics could provide clinically important new information and could help improve our understanding of the pathophysiology of anorectal disorders.

Keywords: Constipation; Fecal incontinence; High-definition anorectal manometry; High-resolution anorectal manometry.

Publication types

  • Review

MeSH terms

  • Anal Canal / physiology
  • Anal Canal / physiopathology
  • Constipation / diagnosis*
  • Constipation / physiopathology
  • Defecation / physiology*
  • Fecal Incontinence / diagnosis*
  • Fecal Incontinence / physiopathology
  • Humans
  • Manometry / instrumentation*
  • Manometry / methods
  • Pressure
  • Rectal Diseases / diagnosis*
  • Rectal Diseases / physiopathology
  • Rectum / physiology
  • Rectum / physiopathology