Phase I dose-escalation study of brentuximab-vedotin combined with dexamethasone, high-dose cytarabine and cisplatin, as salvage treatment in relapsed/refractory classical Hodgkin lymphoma: The HOVON/LLPC Transplant BRaVE study

Haematologica. 2019 Apr;104(4):e151-e153. doi: 10.3324/haematol.2018.196899. Epub 2018 Oct 31.
No abstract available

Publication types

  • Clinical Trial, Phase I
  • Letter
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Brentuximab Vedotin / administration & dosage
  • Brentuximab Vedotin / adverse effects
  • Cisplatin / administration & dosage
  • Cisplatin / adverse effects
  • Cytarabine / administration & dosage
  • Cytarabine / adverse effects
  • Dexamethasone / administration & dosage
  • Dexamethasone / adverse effects
  • Disease-Free Survival
  • Female
  • Hodgkin Disease / drug therapy*
  • Hodgkin Disease / mortality*
  • Hodgkin Disease / pathology
  • Humans
  • Male
  • Middle Aged
  • Recurrence
  • Salvage Therapy*
  • Survival Rate

Substances

  • Cytarabine
  • Dexamethasone
  • Brentuximab Vedotin
  • Cisplatin