Growth Hormone Discovery and Structure

Mat Buchman; Stephen Bell; John J Kopchick

doi:10.17458/per.vol16.2018.bbk.ghdiscoverystructure

Growth Hormone Discovery and Structure

Pediatr Endocrinol Rev. 2018 Sep;16(Suppl 1):2-10. doi: 10.17458/per.vol16.2018.bbk.ghdiscoverystructure.

Authors

Mat Buchman¹, Stephen Bell¹, John J Kopchick²

Affiliations

¹ Heritage College of Osteopathic Medicine, Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA.
² Heritage College of Osteopathic Medicine, Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA, E-mail: kopchick@ohio.edu.

PMID: 30378777
DOI: 10.17458/per.vol16.2018.bbk.ghdiscoverystructure

Abstract

The purpose of this review is to describe and document the discovery of growth hormone (GH) and various activities associated with it. Crucial to this discourse will be a chronicle of results related to the structure of GH. Many individuals were instrumental in the early and current work. Throughout the review we present glimpses into their scientific lives as it affects the evolution of GH's story. We realize that we have not presented a comprehensive review of GH's history and its current and future status, and apologize for the omission of many individuals who contributed to this story.

Keywords: Acromegaly; Action; Discovery; Function; Growth hormone; History; Somatomedin; Structure.

Publication types

Review

MeSH terms

Growth Hormone / metabolism*
Humans
Insulin-Like Growth Factor I

Substances

Insulin-Like Growth Factor I
Growth Hormone