Esophageal Mycobacterium avium-intracellulare infection in a bone marrow transplant patient: Case report and literature review

Transpl Infect Dis. 2019 Feb;21(1):e13019. doi: 10.1111/tid.13019. Epub 2018 Nov 19.

Abstract

Mycobacterium avium-intracellulare complex (MAC) is the most common cause of nontuberculous mycobacterial (NTM) disease in humans. We report a case of esophageal MAC disease in a patient who had allogeneic bone marrow transplant for acute lymphoblastic leukemia. Although pulmonary MAC in immunocompromised host is not uncommon, there are only a few cases of NTM-associated esophageal mass reported. Our report and literature review highlight the importance of considering MAC in the differential diagnosis of dysphagia or odynophagia.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Biopsy
  • Bone Marrow Transplantation / adverse effects*
  • Deglutition Disorders / diagnosis
  • Diagnosis, Differential
  • Esophageal Mucosa / microbiology
  • Esophageal Mucosa / pathology
  • Esophagitis / diagnosis*
  • Esophagitis / microbiology
  • Esophagitis / pathology
  • Esophagoscopy
  • Graft Rejection / immunology
  • Graft Rejection / prevention & control
  • Humans
  • Immunocompromised Host
  • Immunosuppression Therapy / adverse effects
  • Immunosuppression Therapy / methods
  • Male
  • Mycobacterium avium Complex / isolation & purification*
  • Mycobacterium avium-intracellulare Infection / diagnosis*
  • Mycobacterium avium-intracellulare Infection / microbiology
  • Mycobacterium avium-intracellulare Infection / pathology
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / microbiology
  • Postoperative Complications / pathology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / surgery