An update on gastrointestinal disturbances in eating disorders

Larissa Hetterich; Isa Mack; Katrin E Giel; Stephan Zipfel; Andreas Stengel

doi:10.1016/j.mce.2018.10.016

An update on gastrointestinal disturbances in eating disorders

Mol Cell Endocrinol. 2019 Nov 1:497:110318. doi: 10.1016/j.mce.2018.10.016. Epub 2018 Oct 22.

Authors

Larissa Hetterich¹, Isa Mack¹, Katrin E Giel¹, Stephan Zipfel¹, Andreas Stengel²

Affiliations

¹ Department of Psychosomatic Medicine and Psychotherapy, Medical University Hospital Tübingen, Tübingen, Germany.
² Department of Psychosomatic Medicine and Psychotherapy, Medical University Hospital Tübingen, Tübingen, Germany; Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany. Electronic address: andreas.stengel@med.uni-tuebingen.de.

PMID: 30359760
DOI: 10.1016/j.mce.2018.10.016

Abstract

Eating disorders, namely anorexia nervosa, bulimia nervosa and binge eating disorder are frequent diseases and often complicated by comorbidities, e.g. psychiatric or cardiovascular comorbidities. It is to note that also gastrointestinal symptoms/complications are frequently observed in patients with eating disorders. These diseases will be presented in the current review along with - where known - possible underlying mechanisms. Lastly, gaps in knowledge will be highlighted.

Keywords: Functional dyspepsia; Gut-brain axis; Irritable bowel syndrome; Obesity; Psychogastroenterology; Psychosomatic; Stress.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Comorbidity
Feeding and Eating Disorders / complications*
Gastrointestinal Diseases / complications*
Humans
Models, Biological