Dynamic thermal imaging on actinic keratosis patients: A preliminary study

Skin Res Technol. 2019 Mar;25(2):211-216. doi: 10.1111/srt.12640. Epub 2018 Oct 25.

Abstract

Background: Diagnosis of actinic keratosis (AK) based only on clinical findings can be misleading, and histopathological diagnosis results in scars. Dynamic thermal imaging is a potential non-invasive tool for the diagnosis of AK. This imaging technique quantifies the infrared (IR) radiation emitted by a subject after exposure to external thermal stimuli, such as heat or cold.

Methods: Twenty-six histopathologically confirmed AK patients participated in the study. We compared the dynamic thermal images of AK lesions and normal skin (control sites). Temperature changes were plotted as a thermal response graph. After fitting exponential curves to the thermal response graph, the curve was converted to a logarithmic form.

Results: Comparison of the early thermal response graphs of lesions and control sites showed faster thermal recovery of AK lesions. There was a significant difference in the gradient component of the calculated logarithmic equation between the AK lesions and control sites (P < 0.001).

Conclusion: Dynamic thermal imaging can be used as an auxiliary diagnostic tool for AK.

Keywords: actinic keratosis; dynamic thermal imaging; solar keratosis; thermal imaging; thermography.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Algorithms
  • Female
  • Humans
  • Infrared Rays / adverse effects
  • Keratosis, Actinic / diagnostic imaging*
  • Keratosis, Actinic / metabolism
  • Keratosis, Actinic / pathology
  • Male
  • Middle Aged
  • Republic of Korea / epidemiology
  • Skin Neoplasms / diagnostic imaging*
  • Skin Neoplasms / metabolism
  • Skin Neoplasms / pathology
  • Thermography / methods*