[Chemcial constituents of Eclipta prostrata]

Zhongguo Zhong Yao Za Zhi. 2018 Sep;43(17):3498-3505. doi: 10.19540/j.cnki.cjcmm.20180625.001.
[Article in Chinese]

Abstract

A total of twenty-two compounds were isolated from the 95% EtOH extract of Eclipta prostrata by various purification steps, and their structures were established as ecliptalignin A (1),ecliptasaponin Ⅰ (2), ecliptasaponin Ⅱ (3), echinocystic acid (4), 3-oxo-16α-hydroxy-olean-12-en-28-oic acid (5), acacetin-7-O-rutinoside (6), luteoloside (7), apigenin (8), luteolin (9), acacetin (10), skullcapflavone Ⅱ (11), kaempferol (12), kaempferide (13), quercetin (14), 4',7-dihydroxyl-3',6'-dimethoxylisoflavone-7-O-glucoside (15), ecliptal (16), 5-hydroxymethyl-(2,2',5',2″)-terthienyl tiglate (17), psoralen (18), isopsoralen (19), wedelolactone (20), crinumaquine (21), and 2,3,9,12-tetramethoxyprotoberberine (22) mainly based on the spectroscopic techniques, of which 1 was a new lignin analogue, and 5, 6, 10-13, 15, 18, 19, 21 and 22 were isolated form this plant for the first time.

Keywords: Asteraceae; Eclipta prostrata; alkaloid; coumarin; flavone; lignin; pentacyclic triterpene; thiophene.

MeSH terms

  • Eclipta / chemistry*
  • Flavones / analysis
  • Flavones / isolation & purification
  • Lignin / analysis
  • Lignin / isolation & purification
  • Phytochemicals / analysis*
  • Phytochemicals / isolation & purification
  • Saponins / analysis
  • Saponins / isolation & purification

Substances

  • Flavones
  • Phytochemicals
  • Saponins
  • Lignin