Fimbriae and related receptors for Salmonella Enteritidis

Microb Pathog. 2019 Jan:126:357-362. doi: 10.1016/j.micpath.2018.10.025. Epub 2018 Oct 19.

Abstract

Infection with Salmonella Enteritidis (SE) is one of the main causes for food- and water-borne diseases, and is a major concern to public health for both humans and animals worldwide. Some fimbrial antigens expressed by SE strains have been described and characterized, containing SEF14, SEF17, SEF21, long polar fimbriae and plasmid-encoded fimbriae, they play a role in bacterial survival in the host or external environment. However, their functions remain to be well elucidated, with the initial attachment and binding for fimbriae-mediated SE infections only minimally understood. Meanwhile, host-pathogen interactions provide insights into receptor modulation of the host innate immune system. Therefore, to well understand the pathogenicity of SE bacteria and to comprehend the host response to infection, the host cell-SE interactions need to be characterized. This review describes SE fimbriae receptors with an emphasis on the interaction between the receptor and SE fimbriae.

Keywords: Fimbriae; Immunity; Receptor; Salmonella enteritidis.

Publication types

  • Review

MeSH terms

  • Antigens, Bacterial / genetics
  • Antigens, Bacterial / metabolism
  • Bacterial Adhesion / physiology
  • Fimbriae Proteins / genetics
  • Fimbriae Proteins / metabolism*
  • Fimbriae, Bacterial / genetics
  • Fimbriae, Bacterial / metabolism*
  • Host-Pathogen Interactions / immunology
  • Immunity
  • Immunity, Innate
  • Multigene Family
  • Receptors, Immunologic*
  • Salmonella Infections / immunology*
  • Salmonella enteritidis / genetics
  • Salmonella enteritidis / metabolism*

Substances

  • Antigens, Bacterial
  • Receptors, Immunologic
  • sefA protein, Salmonella enteritidis
  • Fimbriae Proteins