Coronary artery ectasia in Crohn's disease

BMJ Case Rep. 2018 Oct 21:2018:bcr2018226813. doi: 10.1136/bcr-2018-226813.

Abstract

Coronary artery ectasia (CAE) can be ascribed, in the majority of cases, to coronary atherosclerosis. Nevertheless, the presence of isolated ectatic lesions without obstructive coronary artery disease and the association of CAE with several autoimmune diseases characterised by systemic vascular involvement suggest that the pathogenesis of CAE may extend beyond coronary atherosclerosis. We herein report the case of a 56-year-old male patient with Crohn's disease and isolated CAE, who has been found positive for IgM and IgA antiendothelial cell antibodies, and discuss a potential pathogenic mechanism.

Keywords: Crohn’s disease; interventional cardiology.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Coronary Angiography
  • Coronary Artery Disease / complications
  • Coronary Artery Disease / diagnosis*
  • Coronary Artery Disease / diagnostic imaging
  • Crohn Disease / complications
  • Crohn Disease / diagnosis*
  • Crohn Disease / diagnostic imaging
  • Crohn Disease / drug therapy
  • Diagnosis, Differential
  • Dilatation, Pathologic
  • Humans
  • Male
  • Mesalamine / therapeutic use
  • Middle Aged
  • Platelet Aggregation Inhibitors / therapeutic use

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Platelet Aggregation Inhibitors
  • Mesalamine