Bowel Preparation for Colorectal Procedures: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines [Internet]

Excerpt

While there is some evidence that suggests that mechanical bowel preparation (MBP) should not be used alone, there is renewed interested in determining the role of MBP, together with preoperative oral antibiotics. Recent retrospective analyses of large databases have suggested that there is an important role for the combination of MBP and oral antibiotics in reducing postoperative surgical site infections in elective colorectal surgery. The objective of this report is to review the clinical effectiveness, cost-effectiveness, and evidence-based guidelines related to intravenous antibiotic prophylaxis (alone) compared to intravenous antibiotics plus oral prophylaxis and/or MBP.