Generation of induced pluripotent stem cells (iPSCs) from human foreskin fibroblasts

Friedrich Erdlenbruch; Jürgen Rohwedel; Philipp Ralfs; Antonia Thomitzek; Jan Kramer; Figen Cakiroglu

doi:10.1016/j.scr.2018.10.010

Generation of induced pluripotent stem cells (iPSCs) from human foreskin fibroblasts

Stem Cell Res. 2018 Dec:33:79-82. doi: 10.1016/j.scr.2018.10.010. Epub 2018 Oct 6.

Authors

Friedrich Erdlenbruch¹, Jürgen Rohwedel², Philipp Ralfs¹, Antonia Thomitzek¹, Jan Kramer¹, Figen Cakiroglu¹

Affiliations

¹ Institute for Virology and Cell Biology, University of Lübeck, Germany.
² Institute for Virology and Cell Biology, University of Lübeck, Germany. Electronic address: juergen.rohwedel@uni-luebeck.de.

PMID: 30321832
DOI: 10.1016/j.scr.2018.10.010

Abstract

The human iPS cell line VUZUZLi001-A (hVH-1) was generated from human foreskin fibroblasts to be used as a control line. Reprogramming was performed by retroviral transduction of reprogramming factors OCT4, SOX2, KLF4 and c-MYC. Resource table.

MeSH terms

Fibroblasts / metabolism*
Foreskin / metabolism*
Humans
Induced Pluripotent Stem Cells / metabolism*
Kruppel-Like Factor 4
Male