Carbon Monoxide Dehydrogenases

Jae-Hun Jeoung; Berta M Martins; Holger Dobbek

doi:10.1007/978-1-4939-8864-8_3

Carbon Monoxide Dehydrogenases

Methods Mol Biol. 2019:1876:37-54. doi: 10.1007/978-1-4939-8864-8_3.

Authors

Jae-Hun Jeoung¹, Berta M Martins¹, Holger Dobbek²

Affiliations

¹ Institute of Biology, Structural Biology and Biochemistry, Humboldt-Universität zu Berlin, Berlin, Germany.
² Institute of Biology, Structural Biology and Biochemistry, Humboldt-Universität zu Berlin, Berlin, Germany. holger.dobbek@hu-berlin.de.

PMID: 30317473
DOI: 10.1007/978-1-4939-8864-8_3

Abstract

Carbon monoxide dehydrogenases (CODHs) catalyze the reversible oxidation of CO with water to CO₂, two electrons, and two protons. Two classes of CODHs exist, having evolved from different scaffolds featuring active sites built from different transition metals. The basic properties of both classes are described in this overview chapter.

Keywords: CO2; Carbon monoxide dehydrogenase; Iron–sulfur clusters; Ni enzymes; cluster C.

Publication types

Review

MeSH terms

Aldehyde Oxidoreductases / chemistry*
Aldehyde Oxidoreductases / classification
Aldehyde Oxidoreductases / metabolism*
Anaerobiosis
Archaea / enzymology
Bacteria, Anaerobic / enzymology
Carbon Monoxide / metabolism*
Catalytic Domain
Evolution, Molecular
Models, Molecular
Multienzyme Complexes / chemistry*
Multienzyme Complexes / classification
Multienzyme Complexes / metabolism*
Protein Conformation

Substances

Multienzyme Complexes
Carbon Monoxide
Aldehyde Oxidoreductases
carbon monoxide dehydrogenase