Several intraocular infections can present with protean manifestations posing major diagnostic and management challenges. Infections such as tuberculosis, dengue and chikungunya fever have continued to remain major endemic diseases that are associated with uveitis in the Asia Pacific region. These entities often require a high index of clinical suspicion and laboratory analysis including assays of ocular fluids and/or tissues for confirmation of the diagnosis. Infectious uveitis caused by tuberculosis, dengue and chikungunya can present with characteristic clinical features and imaging findings on ancillary investigations; that may provide clue to the early diagnosis. Use of modern imaging modalities such as enhanced-depth imaging optical coherence tomography, optical coherence tomography angiography and ultra-wide field fundus photography greatly aid in the evaluation of these conditions. In the current review, we have discussed the epidemiology, clinical phenotypes, imaging characteristics, diagnosis and management of uveitis caused by tuberculosis, dengue and chikungunya.
摘要: 眼内感染的临床表现多种多样, 是目前诊断和治疗的主要挑战。结核病, 登革热和基孔肯雅热感染仍是亚太地区与葡萄膜炎相关的主要地方性疾病。这些感染临床需要高度重视和实验室检查, 包括眼部液体和或组织检查以确诊。由结核病, 登革热和基孔肯雅病引起的传染性葡萄膜炎可能具有一些特征性的临床表现和特殊的影像学表现, 这些都可为早期诊断提供线索。现代成像技术的应用, 包括光学相干断层扫描增强深度成像模式、光学相干断层扫描血管造影和超广角眼底成像, 极大地提高了诊断和评估传染性葡萄膜炎准确性。在这篇综述中, 我们讨论了由结核病, 登革热和基孔肯雅热引起的葡萄膜炎的流行病学, 临床表型, 影像学特征以及诊断和治疗。.