Coronary Artery Bypass Grafting with Arterial Grafts in Patients with Kawasaki Disease Affecting the Coronary Artery: a Korean Single-Center Study

J Korean Med Sci. 2018 Sep 17;33(42):e267. doi: 10.3346/jkms.2018.33.e267. eCollection 2018 Oct 15.

Abstract

Background: This study aimed to review the long-term clinical outcomes and graft patency of coronary artery bypass grafting (CABG) using arterial grafts in patients with Kawasaki disease (KD) affecting the coronary artery.

Methods: Twenty patients with KD who underwent CABG from January 2002 to June 2014 were enrolled. There were 4 male (20%) and 16 female (80%) patients with ages at operation ranging from 2 to 42 years (median, 17.5 years). Our routine operative strategy was off-pump CABG with arterial grafts. The mean follow-up duration was 59.5 ± 48.5 months (range, 1-159 months). Coronary angiogram or computed tomography angiogram was used to evaluate graft patency in 16 patients (80%).

Results: All patients survived CABG without late mortality. Left internal thoracic arteries were used in 19 patients, while right internal thoracic arteries were used in 10 patients. Right gastroepiploic arteries were used in 3 patients, and a saphenous vein graft (SVG) was used in 1 patient. Among the 20 patients, 2 patients underwent coronary reintervention with balloon angioplasty because of graft failure. Two patients underwent coronary reintervention because of new obstructive lesions that were not significant at the time of the initial operation. Patency rates at 5 and 10 years were 94% and 87%, respectively. The rate of freedom from coronary reintervention at 10 years was 82%.

Conclusion: Off-pump CABG with mainly arterial graft revascularization may be considered a good surgical option for coronary lesions caused by KD.

Keywords: Coronary Artery Bypass Grafting; Graft; Kawasaki Disease.

MeSH terms

  • Adolescent
  • Adult
  • Angioplasty, Balloon
  • Child
  • Child, Preschool
  • Coronary Artery Bypass*
  • Coronary Artery Bypass, Off-Pump
  • Coronary Vessels / surgery*
  • Female
  • Humans
  • Male
  • Mucocutaneous Lymph Node Syndrome / pathology
  • Mucocutaneous Lymph Node Syndrome / therapy*
  • Republic of Korea
  • Retrospective Studies
  • Young Adult