This chapter intends to provide an overview of computer-assisted minimally invasive spine surgery (CAMISS) and its clinical application. Since minimally invasive spine surgery was first brought out, the concept of decreasing the damage to patient was soon become popular. However, without the proper surgical field, the spine surgery can be very dangerous. The minimally invasive concept was restricted in promotion until the computer-assisted navigation system break down the obstacles. The CAMISS technique achieves better clinical outcomes with the advantages of smaller invasion, less injury, and better recovery and also became the gold standard for spine surgery. The spatial distribution concept and the respiration-induced motion concept help in promoting the accuracy and safety of the CAMISS concept. The CAMISS concept also facilitated the developing of robotic techniques, which was considered as the future of orthopedic surgery.
Keywords: Clinical applications; Computer-assisted minimally invasive spine surgery (CAMISS); Computer-assisted navigation; Intelligent orthopedics; Medical robotics.