Entering the Pocket: Crystal Structure of a Prostaglandin D2 Receptor

Mithu Baidya; Punita Kumari; Arun K Shukla

doi:10.1016/j.molcel.2018.09.024

Entering the Pocket: Crystal Structure of a Prostaglandin D2 Receptor

Mol Cell. 2018 Oct 4;72(1):3-6. doi: 10.1016/j.molcel.2018.09.024.

Authors

Mithu Baidya¹, Punita Kumari¹, Arun K Shukla²

Affiliations

¹ Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 2018016, India.
² Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 2018016, India. Electronic address: arshukla@iitk.ac.in.

PMID: 30290148
DOI: 10.1016/j.molcel.2018.09.024

Abstract

In this issue of Molecular Cell, crystal structures of a prostaglandin D2 receptor determined by Wang et al. (2018) reveal novel insights into differential ligand recognition among the members of lipid-binding GPCRs, and provide a structural framework for the identification of novel therapeutics in inflammatory disorders.

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MeSH terms

Humans
Ligands
Receptors, Immunologic*
Receptors, Prostaglandin*

Substances

Ligands
Receptors, Immunologic
Receptors, Prostaglandin
prostaglandin D2 receptor