Analysis of corneal higher-order aberrations in cataract patients with high myopia

J Cataract Refract Surg. 2018 Dec;44(12):1482-1490. doi: 10.1016/j.jcrs.2018.07.048. Epub 2018 Sep 28.

Abstract

Purpose: To evaluate the differences in corneal higher-order aberrations (HOAs) between cataract patients with high axial myopia and normal cataract patients, and to identify the associated factors.

Setting: Department of Ophthalmology and Vision Science of the Eye and ENT Hospital of Fudan University, Shanghai, China.

Design: Retrospective case series.

Methods: Corneal aberrations and axial lengths (ALs) were measured using a rotating Scheimpflug camera (Pentacam) and partial coherence interferometry (IOLMaster) in the high myopia group and the control group.

Results: The study comprised 287 patients (520 eyes). There were 194 eyes in the high myopia group and 326 eyes in the control group. The 5 anterior corneal aberrations-vertical coma, vertical trefoil, horizontal coma, oblique trefoil, and primary spherical aberration-in the high myopia group were 0.07 μm ± 0.38 (SD), -0.11 ± 0.23 μm, 0.07 ± 0.28 μm, -0.02 ± 0.18 μm, and 0.39 ± 0.19 μm, respectively. No negative primary spherical aberrations of the total or anterior corneal surface were found in the high myopia group. Differences between the 2 groups were found in terms of central corneal thickness, astigmatism, primary spherical aberration, vertical coma, and oblique trefoil; however, these differences were not consistent between different age subgroups. Higher-order aberrations were correlated with age. Posterior corneal vertical coma was correlated with AL (Pearson correlation = -0.188, P = .047).

Conclusions: Negative primary spherical aberrations of the anterior or total corneal surface were not found in the high myopia group. Age showed a strong relationship with HOAs. For cataract patients with high myopia, aspheric intraocular lens implantation is recommended.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Cataract / complications*
  • Cataract / diagnosis
  • Cataract / physiopathology
  • Cornea / diagnostic imaging*
  • Corneal Topography / methods*
  • Corneal Wavefront Aberration / complications
  • Corneal Wavefront Aberration / diagnosis*
  • Corneal Wavefront Aberration / physiopathology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myopia / complications
  • Myopia / diagnosis*
  • Myopia / physiopathology
  • Retrospective Studies
  • Visual Acuity*
  • Young Adult