Recurrence of venous thromboembolism (VTE) is seen in approximately one third of the patients after discontinuation of therapy with anticoagulants. The duration of treatment seems to be of minor importance, as several studies have shown the same recurrence rate over years after treatment for three months and up to 24 months. In patients with reversible risk factors, three months of treatment seems to be sufficient. Treatment duration should be determined by physicians with special expertise in risk factors for VTE recurrence and bleeding complications.