Venous thrombosis in unusual sites: A practical review for the hematologist

Eur J Haematol. 2019 Jan;102(1):53-62. doi: 10.1111/ejh.13177. Epub 2018 Oct 29.

Abstract

Thrombosis of unusual venous sites encompasses a large part of consultative hematology and is encountered routinely by practicing hematologists. Contrary to the more commonly encountered lower extremity venous thrombosis and common cardiovascular disorders, the various thromboses outlined in this review have unique presentations, pathophysiology, workup, and treatments that all hematologists should be aware of. This review attempts to outline the most up to date literature on cerebral, retinal, upper extremity, hepatic, portal, splenic, mesenteric, and renal vein thrombosis, focusing on the incidence, pathophysiology, provoking factors, and current recommended treatments for each type of unusual thrombosis to provide a useful and practical review for the hematologist.

Keywords: anticoagulation; coagulation disorder; hypercoagulable; venous thrombosis.

Publication types

  • Review

MeSH terms

  • Budd-Chiari Syndrome / diagnosis
  • Budd-Chiari Syndrome / etiology
  • Budd-Chiari Syndrome / therapy
  • Cerebral Veins / pathology
  • Disease Management
  • Humans
  • Mesenteric Veins / pathology
  • Portal Vein / pathology
  • Renal Veins / pathology
  • Retinal Vein / pathology
  • Splenic Vein / pathology
  • Upper Extremity / pathology
  • Venous Thrombosis / diagnosis*
  • Venous Thrombosis / etiology
  • Venous Thrombosis / therapy*