Research Progress on the Toxic Antagonism of Selenium Against Mycotoxins

Biol Trace Elem Res. 2019 Jul;190(1):273-280. doi: 10.1007/s12011-018-1532-6. Epub 2018 Sep 29.

Abstract

Animal feed is prone to becoming infected with molds during production and storage, resulting in secondary metabolite mycotoxins, such as aflatoxin B1 (AFB1), T-2 toxins, deoxynivalenol (DON), and ochratoxin A (OTA), which are harmful to humans and animals. Selenium is an essential trace element for humans and animals, and it is also an effective antioxidant. Many studies have shown that selenium can reduce the damage caused by mycotoxins in animals. This article reviews the current literature on the antagonistic effects of selenium on AFB1, T-2, DON, and OTA toxicity.

Keywords: Antagonism; Mycotoxins; Selenium.

Publication types

  • Review

MeSH terms

  • Aflatoxin B1 / chemistry
  • Animal Feed / analysis*
  • Mycotoxins / chemistry*
  • Ochratoxins / chemistry
  • Selenium / chemistry*
  • Trichothecenes / chemistry

Substances

  • Mycotoxins
  • Ochratoxins
  • Trichothecenes
  • ochratoxin A
  • Aflatoxin B1
  • Selenium
  • deoxynivalenol