In experiment on animals, in which the cold trauma was simulated, the systemic inflammatory reactions indices—level of С—reactive protein, аctive products of thiobarbituric acid the blood serum, erythrocyte sedimentation rate (ESR), leukocyte blood formula (LBF) while injection of placenta extract — were studied. C—reactive protein level lowering in 1.3 times on the 14—th day of experiment, reduction of ESR in 1.6 times on the 7—th and 14—th day, LBF normalization on the 7—th day, lowering of the аctive products of thiobarbituric acid level in 1.3 times on the 7, 9—th and 14—th day of observation were noted. On the 21—st day all the indices came back to norm.