Surface-Active Fluorinated Quantum Dots for Enhanced Cellular Uptake

Chemistry. 2019 Jan 2;25(1):195-199. doi: 10.1002/chem.201804704. Epub 2018 Nov 20.

Abstract

Fluorescent nanoparticles, such as quantum dots, hold great potential for biomedical applications, mainly sensing and bioimaging. However, the inefficient cell uptake of some nanoparticles hampers their application in clinical practice. Here, the effect of the modification of the quantum dot surface with fluorinated ligands to increase their surface activity and, thus, enhance their cellular uptake was explored.

Keywords: Langmuir monolayer; cell uptake; fluorine; quantum dots; surface activity.