Unlocking a dark past

Fernando Rodríguez-Pérez; Michael Rape

doi:10.7554/eLife.41002

Unlocking a dark past

Elife. 2018 Sep 25:7:e41002. doi: 10.7554/eLife.41002.

Authors

Fernando Rodríguez-Pérez^{1

2}, Michael Rape^{1

2}

Affiliations

¹ Howard Hughes Medical Institute, University of California, Berkeley, United States.
² Department of Molecular and Cell Biology, University of California, Berkeley, United States.

Abstract

A transcription factor called SALL4 could be the missing link between thalidomide and the limb defects caused by the drug.

Keywords: Chemical Biology; Teratogenicity; Thalidomide; Transcription Factors; Ubiquitin; biochemistry; chemical biology; developmental biology; human.

Publication types

Comment

MeSH terms

Humans
Limb Deformities, Congenital
Teratogens*
Thalidomide*
Transcription Factors

Substances

Teratogens
Transcription Factors
Thalidomide