Secukinumab for plaque psoriasis with ocular comorbidity: a clinical experience

J Dermatolog Treat. 2018;29(sup1):9-11. doi: 10.1080/09546634.2018.1527995.

Abstract

Psoriasis is a systemic inflammatory disorder associated with many other chronic and progressive diseases. Ocular comorbidity has been reported in 10-15% of patients with plaque psoriasis, but the real incidence is still underestimated. This paper reports successful treatment with secukinumab of a patient with plaque psoriasis and dry eye syndrome. Secukinumab treatment was rapidly effective on skin psoriasis and this result was in agreement with observations reported in the literature. Interestingly, both the skin condition and the ocular disease improved after treatment. Our experience suggests that this drug should be used in patients with plaque psoriasis and ophthalmologic manifestations.

Keywords: Psoriasis; dry eye syndrome; secukinumab.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized
  • Comorbidity
  • Dermatologic Agents / therapeutic use*
  • Dry Eye Syndromes / epidemiology*
  • Female
  • Humans
  • Psoriasis / drug therapy*
  • Psoriasis / epidemiology
  • Young Adult

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Dermatologic Agents
  • secukinumab