Control and elimination of rabies in Croatia

PLoS One. 2018 Sep 20;13(9):e0204115. doi: 10.1371/journal.pone.0204115. eCollection 2018.

Abstract

Despite the implementation of control measures (preventive dog vaccination), rabies has become endemic in Croatia, with red foxes being the main reservoir species. Oral rabies vaccination (ORV) campaigns supported by the European Commission have been conducted twice a year since the spring of 2011. The first campaigns were limited to the northern and eastern parts of the country, and from the autumn of 2012, the program was extended to the entire country. The Lysvulpen vaccine containing the SAD Bern strain was used for ORV. Following the vaccination campaigns, the number of rabies cases decreased, and the last positive case was recorded in February 2014. The bait uptake ranged from 24.86% to 84.62% and the immunisation rate from 11.24% to 35.64%.

MeSH terms

  • Animals
  • Croatia / epidemiology
  • Disease Eradication*
  • Foxes / immunology
  • Foxes / virology
  • Immunity, Humoral
  • Incidence
  • Jackals / immunology
  • Jackals / virology
  • Oxytetracycline / therapeutic use
  • Phylogeny
  • Rabies / drug therapy
  • Rabies / epidemiology*
  • Rabies / immunology
  • Rabies / prevention & control*
  • Rabies virus / physiology
  • Seroconversion

Substances

  • Oxytetracycline

Grants and funding

The authors received no specific funding for this work.