Ocular involvement in atopic disease: a review

Curr Opin Ophthalmol. 2018 Nov;29(6):576-581. doi: 10.1097/ICU.0000000000000532.

Abstract

Purpose of review: To provide a review of the potential sight-threatening sequelae associated with ocular involvement of atopic disease and to discuss the management of this chronic condition.

Recent findings: There has been a recognition that atopic keratoconjunctivitis (AKC) is a chronic, inflammatory and potentially blinding disease. Recent efforts have focused on steroid sparing, systemic T cell and calcineurin inhibitor medications for the treatment of severe disease.

Summary: Ocular involvement in atopic disease can have a variety of clinical manifestations. Progressive disease can be vision threatening, especially in younger patients. Prompt and effective treatment through a multidisciplinary approach, including ophthalmology, allergy and immunology and dermatology, can permit stability of the disease.

Publication types

  • Review

MeSH terms

  • Calcineurin Inhibitors / therapeutic use
  • Conjunctivitis, Allergic* / diagnosis
  • Conjunctivitis, Allergic* / drug therapy
  • Conjunctivitis, Allergic* / physiopathology
  • Humans
  • Treatment Outcome

Substances

  • Calcineurin Inhibitors