The effects of caffeine ingestion on isokinetic muscular strength: A meta-analysis

J Sci Med Sport. 2019 Mar;22(3):353-360. doi: 10.1016/j.jsams.2018.08.016. Epub 2018 Aug 30.

Abstract

Objectives: The aims of this paper are threefold: (1) to summarize the research examining the effects of caffeine on isokinetic strength, (2) pool the effects using a meta-analysis, and (3) to explore if there is a muscle group or a velocity specific response to caffeine ingestion.

Design: Meta-analysis.

Methods: PubMed/MEDLINE, Scopus, and SPORTDiscus were searched using relevant terms. The PEDro checklist was used for the assessment of study quality. A random-effects meta-analysis of standardized mean differences (SMDs) was done.

Results: Ten studies of good and excellent methodological quality were included. The SMD for the effects of caffeine on strength was 0.16 (95% CI=0.06, 0.26; p=0.003; +5.3%). The subgroup analysis for knee extensor isokinetic strength showed a significant difference (p=0.004) between the caffeine and placebo conditions with SMD value of 0.19 (95% CI=0.06, 0.32; +6.1%). The subgroup analysis for the effects of caffeine on isokinetic strength of other, smaller muscle groups indicated no significant difference (p=0.092) between the caffeine and placebo conditions. The subgroup analysis for knee extensor isokinetic strength at angular velocities of 60°s-1 and 180°s-1 showed a significant difference between the caffeine and placebo conditions; however, no significant effect (p=0.193) was found at an angular velocity of 30°s-1.

Conclusions: This meta-analysis demonstrates that acute caffeine ingestion caffeine may significantly increase isokinetic strength. Additionally, this meta-analysis reports that the effects of caffeine on isokinetic muscular strength are predominantly manifested in knee extensor muscles and at greater angular velocities.

Keywords: Caffeine; Exercise; Muscles; Power; Torque.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Caffeine / pharmacology*
  • Humans
  • Knee
  • Muscle Strength / drug effects*
  • Muscle, Skeletal / drug effects*
  • Muscle, Skeletal / physiology
  • Randomized Controlled Trials as Topic

Substances

  • Caffeine