Aripiprazole combination for reversal of paliperidone-induced increase in prolactin level

Neuropsychiatr Dis Treat. 2018 Aug 27:14:2175-2179. doi: 10.2147/NDT.S167129. eCollection 2018.

Abstract

Hyperprolactinemia is a common side effect of antipsychotic drugs. Although changes of antipsychotic drugs or reduction of their doses can solve this problem, a modification of the treatment regimen can lead to instability in patients. Herein, we followed up a patient with elevated prolactin caused by paliperidone and found that the prolactin level was decreased after the administration of a combination with a low-dose aripiprazole. In addition, we summarized and analyzed the findings from the case and the literature review conducted.

Keywords: aripiprazole; prolactin; schizophrenia.

Publication types

  • Case Reports