Association between obesity and mortality in adult patients receiving invasive mechanical ventilation: A systematic review and meta-analysis

Abstract

Objective: To evaluate if there is an association between obesity and mortality in the Intensive Care Unit (ICU) in adult patients receiving invasive mechanical ventilation.

Design: Systematic review with meta-analysis.

Scope: ICU.

Data source: A search was made in MEDLINE, Cochrane Library, CINAHL and Global Health databases without language restriction, until February 21, 2017.

Selection of studies: Studies that reported mortality in the ICU in obese versus non-obese patients who received IMV were included.

Main variables: Mortality in the ICU.

Results: 2163 articles were found, of which 14 studies were included. No statistically significant differences were found between obese and non-obese patients with respect to the variable mortality in the ICU (OR: 0.94, 95% CI: 0.81-1.10, P=.45).

Conclusion: No relationship was found between the subgroup of obese adult patients receiving IMV and the mortality variable in the ICU.

Keywords: Artificial respiration; Intensive care units; Meta-analysis; Metaanálisis; Mortalidad; Mortality; Obesidad; Obesity; Respiración artificial; Unidad de cuidados intensivos.