Set Phasers to Cleave: PIWI Cleavage Directs All piRNA Biogenesis

Mol Cell. 2018 Sep 6;71(5):651-652. doi: 10.1016/j.molcel.2018.08.035.

Authors

Anastassios Vourekas¹, Zissimos Mourelatos²

Affiliations

¹ Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Pennsylvania, Philadelphia, PA 19104, USA.
² Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: mourelaz@uphs.upenn.edu.

PMID: 30193093
DOI: 10.1016/j.molcel.2018.08.035

Abstract

In this issue of Molecular Cell, Gainetdinov et al. (2018) show that PIWI proteins direct both piRNA biogenesis and piRNA function in most animals.

Copyright © 2018. Published by Elsevier Inc.

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MeSH terms

Animals
Proteins*
RNA, Small Interfering

Substances

Proteins
RNA, Small Interfering