[The usefulness of nasal provocation tests for respiratory physicians]

Rev Mal Respir. 2018 Oct;35(8):788-795. doi: 10.1016/j.rmr.2018.06.001. Epub 2018 Aug 31.
[Article in French]

Abstract

Rhinitis and asthma are common diseases that are strongly linked from both the epidemiological and patho-physiological point of view. A precise aetiological diagnosis is required in order to optimize treatment. Nasal provocation tests (NPT) determine precisely the role of the allergen in the initiation of the symptoms of rhinitis particularly when the history does not produce convincing evidence of the clinical relevance of an allergen. It may also have important consequences for the choice of an allergenic immunotherapy. NPT are not standardized but simple methods based on international recommendations provide us with good diagnostic accuracy. In this paper, we will discuss the practical aspects of NPT as well as the clinical or research situations where they may be useful for the respiratory physician.

Keywords: Acariens domestiques; Allergic rhinitis; Asthma; Asthme; House dust mites; Nasal challenge tests; Rhinite allergique; Test de provocation nasale; The naso-bronchial airway; Unité nez-bronche.

Publication types

  • Review

MeSH terms

  • Allergens / administration & dosage
  • Asthma / diagnosis*
  • Humans
  • Nasal Provocation Tests* / methods
  • Nasal Provocation Tests* / standards
  • Practice Patterns, Physicians' / statistics & numerical data
  • Predictive Value of Tests
  • Pulmonary Medicine* / methods
  • Pulmonary Medicine* / standards
  • Rhinitis / diagnosis*
  • Rhinitis, Allergic, Perennial / diagnosis
  • Rhinitis, Allergic, Seasonal / diagnosis
  • Skin Tests

Substances

  • Allergens