Potent biomedical applications of isolated polysaccharides from marine microalgae Tetraselmis species

Bioprocess Biosyst Eng. 2018 Nov;41(11):1611-1620. doi: 10.1007/s00449-018-1987-z. Epub 2018 Aug 22.

Abstract

Microalgae Tetraselmis species were used to evaluate the biological characteristics of water-soluble polysaccharides (WSPs) as one of the significant bioactive substances (BAS) from these photosynthetic microalgae species. Compositional analysis of these BAS shows that they are mainly composed of WSPs along with negligible amount of proteins and lipids. WSPs were partially purified and characterized for their compositional, structural and biological properties such as antioxidant, tyrosinase inhibitory activity and antifungal activies. These WSPs showed the significant antioxidant, antifungal and tyrosinase inhibitory activities, respectively. The outcomes of this study demonstrated that WSPs can be the potent source of biological moieties for further investigations along with specific potent biological activities.

Keywords: Bioactive substances; Biological activities; Photosynthetic microalgae; Water-soluble polysaccharide.

MeSH terms

  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology
  • Biological Products / chemistry
  • Biological Products / isolation & purification
  • Biological Products / pharmacology
  • Biomass
  • Chlorophyta / chemistry*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / isolation & purification
  • Enzyme Inhibitors / pharmacology
  • Microalgae / chemistry*
  • Monophenol Monooxygenase / antagonists & inhibitors
  • Polysaccharides / chemistry
  • Polysaccharides / isolation & purification*
  • Polysaccharides / pharmacology
  • Solubility
  • Water

Substances

  • Antifungal Agents
  • Antioxidants
  • Biological Products
  • Enzyme Inhibitors
  • Polysaccharides
  • Water
  • Monophenol Monooxygenase