Anterior and Intermediate Uveitis Following Yellow Fever Vaccination with Fractional Dose: Case Reports

Ocul Immunol Inflamm. 2019;27(4):521-523. doi: 10.1080/09273948.2018.1510529. Epub 2018 Aug 28.

Abstract

Purpose: To describe two cases of anterior and intermediate uveitis following yellow fever vaccination with fractional dose. Methods: Case report. Results: Case 1: A 35 year-old healthy woman presented with unilateral anterior uveitis 10 days after the yellow fever vaccination. Testing excluded infectious and rheumatic diseases and the episode was fully recovered after a short course of topical treatment. Case 2: A 21 year-old previously healthy woman presented with blurred vision in the left eye (OS) 14 days after the yellow fever vaccination. The ophthalmic examination of the OS revealed intermediated uveitis. Testing excluded infectious and neurological diseases. After six weeks of treatment with oral prednisone, the ocular inflammation had resolved. Conclusion: Physicians should be aware of the possibility of eye inflammation following the yellow fever vaccination.

Keywords: Anterior uveitis; causality; intermediate uveitis; uveitis; yellow fever vaccine.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Administration, Oral
  • Adult
  • Dexamethasone / administration & dosage
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Glucocorticoids / administration & dosage
  • Humans
  • Prednisone / administration & dosage
  • Retina / diagnostic imaging*
  • Uveitis, Anterior / diagnosis
  • Uveitis, Anterior / etiology*
  • Uveitis, Intermediate / diagnosis
  • Uveitis, Intermediate / etiology*
  • Vaccination / adverse effects*
  • Visual Acuity
  • Yellow Fever / prevention & control
  • Yellow Fever Vaccine / adverse effects*
  • Yellow fever virus / immunology
  • Young Adult

Substances

  • Glucocorticoids
  • Yellow Fever Vaccine
  • Dexamethasone
  • Prednisone