Analgesic, anti-inflammatory and diuretic activities of Macrotyloma uniflorum (Lam.) Verdc

Pak J Pharm Sci. 2018 Sep;31(5):1859-1863.

Abstract

Macrotyloma uniflorum (Lam.) Verdc. (Papilionaceae) is commonly known as Horse gram and Kulthi. The seeds are reported as anthelmintic, diaphoretic, diuretic and emmenagogue. It is also useful in asthma, bronchitis and urolithiasis. In the present study, analgesic, anti-inflammatory and diuretic effects of the methanol extract of Macrotyloma uniflorum seeds were evaluated in doses of 200 and 400mg/kg. Significant results were obtained in all activities.

MeSH terms

  • Analgesics / isolation & purification
  • Analgesics / pharmacology
  • Analgesics / therapeutic use*
  • Animals
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use*
  • Diuretics / isolation & purification
  • Diuretics / pharmacology
  • Diuretics / therapeutic use*
  • Dose-Response Relationship, Drug
  • Edema / drug therapy
  • Edema / metabolism
  • Edema / pathology
  • Fabaceae
  • Mice
  • Pain Measurement / drug effects
  • Pain Measurement / methods
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*
  • Rats
  • Rats, Wistar
  • Seeds*

Substances

  • Analgesics
  • Anti-Inflammatory Agents
  • Diuretics
  • Plant Extracts