A holistic approach to the human person, from a somatic, psychological and spiritual point of view, with reference to the harmfulness of alcoholism and smoking in cardiovascular pathology, highlights several therapeutic variants over time. Among them are: the current somatic therapy, which could not offer optimal solution in eradicating this vice, and psychiatry which, using will power, could not solve man’s contradiction with himself, caused by a tempting and treacherous irrationality of senses, instinctive-affective desires, turned into vices, as a “Quasi altera natura”, devoid of any bright and creative horizon. As such we propose an alternative that entails changing one’s lifestyle to eliminate the harmful effect of alcoholism and smoking on cardiovascular pathology, through the perspective of spiritual therapy, accessible to contemporary society, at no cost and with no adverse events.