Microbial conversion of xylose into useful bioproducts

Appl Microbiol Biotechnol. 2018 Nov;102(21):9015-9036. doi: 10.1007/s00253-018-9294-9. Epub 2018 Aug 24.

Abstract

Microorganisms can produce a number of different bioproducts from the sugars in plant biomass. One challenge is devising processes that utilize all of the sugars in lignocellulosic hydrolysates. D-xylose is the second most abundant sugar in these hydrolysates. The microbial conversion of D-xylose to ethanol has been studied extensively; only recently, however, has conversion to bioproducts other than ethanol been explored. Moreover, in the case of yeast, D-xylose may provide a better feedstock for the production of bioproducts other than ethanol, because the relevant pathways are not subject to glucose-dependent repression. In this review, we discuss how different microorganisms are being used to produce novel bioproducts from D-xylose. We also discuss how D-xylose could be potentially used instead of glucose for the production of value-added bioproducts.

Keywords: Bioproducts; Fermentation; Hemicellulose; Metabolic engineering; Xylose.

Publication types

  • Review

MeSH terms

  • Bacteria / metabolism*
  • Biological Products / metabolism*
  • Biomass
  • Ethanol / metabolism
  • Glucose / metabolism
  • Humans
  • Plants / metabolism
  • Plants / microbiology
  • Xylose / metabolism*
  • Yeasts / metabolism*

Substances

  • Biological Products
  • Ethanol
  • Xylose
  • Glucose