Genetic polymorphisms of 21 autosomal STR loci in Chinese Uygur ethnic population

Int J Legal Med. 2018 Nov;132(6):1637-1639. doi: 10.1007/s00414-018-1913-6. Epub 2018 Aug 20.

Abstract

Genetic polymorphisms of 21 short tandem repeat (STR) loci were studied in 576 unrelated Uygur individuals living in Urumqi using Goldeneye™ DNA ID 22NC system. Population data of all loci, except one locus (D1S1656), had no significant deviation from Hardy-Weinberg equilibrium. A high degree of genetic polymorphisms was showed by all STR loci in Urumchi Uygur population. The combined power of discrimination (CPD) was 0.999999999999999999999999985256 and the combined power of exclusion (CPE) was 0.999999997207836. In addition, we performed comparisons between the data from Uygur population with previously published data obtained from other populations.

Keywords: Autosomal short tandem repeats; Goldeneye™ DNA ID 22NC system; Population genetics; Uygur ethnic.

MeSH terms

  • China
  • DNA Fingerprinting
  • Ethnicity / genetics*
  • Gene Frequency
  • Genetics, Population*
  • Humans
  • Microsatellite Repeats*
  • Polymerase Chain Reaction
  • Polymorphism, Genetic*