[A cutaneous case of angiolymphoid hyperplasia with eosinophilia: Presentation of a rare entity]

Ann Pathol. 2018 Dec;38(6):386-390. doi: 10.1016/j.annpat.2018.06.002. Epub 2018 Aug 16.
[Article in French]

Abstract

We report the case of a Caucasian 73-year-old woman, without medical history, who is operated of two lesions of the forehead and the scalp measuring 0.4 and 1cm. There is no adenopathy. Histopathological examination revealed a diffuse vascular proliferation of the dermis and the hypodermis composed of small vessels bordered of plump "epthelioid" endothelial cells. There is no mitotic figure. The stroma is slightly fibrous accompanied by a polymorphic inflammatory infiltrate rich in lymphocytes, sometimes arranged in lymphoid follicles, plasma cells and eosinophils. The proposed diagnosis is angiolymphoid hyperplasia with eosinophilia. This is a rare vascular tumor, benign according with the OMS classification and preferentially observed in the skin. We report a cutaneous case, clinical and histopathological data of the reported cases and present the main differential diagnoses.

Keywords: Angiolymphoid hyperplasia; Eosinophils; Hyperplasie angiolymphoïde; Éosinophiles.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Angiolymphoid Hyperplasia with Eosinophilia / diagnosis
  • Angiolymphoid Hyperplasia with Eosinophilia / epidemiology
  • Angiolymphoid Hyperplasia with Eosinophilia / pathology*
  • Angiomatosis, Bacillary / diagnosis
  • Diagnosis, Differential
  • Facial Neoplasms / diagnosis
  • Facial Neoplasms / pathology
  • Female
  • Forehead
  • Head and Neck Neoplasms / diagnosis
  • Head and Neck Neoplasms / pathology*
  • Hemangioma / diagnosis
  • Hemangioma / epidemiology
  • Hemangioma / pathology*
  • Humans
  • Inflammation
  • Lymphocytes / pathology
  • Lymphoma, Non-Hodgkin / diagnosis
  • Plasma Cells / pathology
  • Scalp / pathology*
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / epidemiology
  • Skin Neoplasms / pathology*