Observation of the cytoarchitecture of the human esophageal mucosa with special attention to the lamina muscularis mucosae and the distribution of lymphatic vessels

Esophagus. 2019 Jan;16(1):44-51. doi: 10.1007/s10388-018-0632-x. Epub 2018 Aug 2.

Abstract

The cytoarchitecture of the esophageal mucosa was examined by using light microscopy, transmission electron microscopy, and scanning electron microscopy. The cytoarchitecture of the muscularis mucosae varied greatly among the cervical, thoracic, and abdominal esophagus, especially in the cervical esophagus, the muscularis mucosae suffered a loss and the distribution of lymphatic vessels also varied according to the site. It was suggested that these morphological differences would have a strong influence on the infiltration of esophageal cancer and the mode of lymph node metastasis.

Keywords: Esophagus; Lamina muscularis mucosae; Lymphatic vessels.

MeSH terms

  • Esophageal Mucosa / immunology
  • Esophageal Mucosa / ultrastructure*
  • Esophageal Neoplasms / pathology
  • Esophageal Neoplasms / ultrastructure
  • Humans
  • Lymphatic Metastasis
  • Lymphatic Vessels / immunology
  • Lymphatic Vessels / ultrastructure*
  • Microscopy, Electron
  • Microscopy, Electron, Scanning
  • Muscle, Smooth / ultrastructure
  • Neoplasm Invasiveness