Association of anemia and malnutrition in hospitalized patients with exclusive enteral nutrition

Nutr Hosp. 2018 Jun 22;35(4):753-760. doi: 10.20960/nh.1628.

Abstract

Introduction: enteral nutrition therapy maintains and/or regains the nutritional status of the common patient in hospital settings, where anemia and malnutrition are food related and are very common diseases.

Objective: to determine and associate the presence of anemia and malnutrition in hospitalized patients with exclusive enteral nutrition.

Methods: a prospective, cross-sectional study with patients receiving exclusive enteral nutrition up to 72 hours after hospitalization. A nutritional evaluation was performed, consisting of anthropometric data, such as weight, circumferences, and skinfolds; dietary evaluation (data were collected through an electronic medical record) and biochemistry data (hemogram, albumin, C-reactive protein, capillary glucose monitoring).

Results: the population consists of 77 individuals. As the patients presented greater severity of anemia, corrected arm muscle area, calf circumference and serum albumin levels were reduced while C-reactive protein increased significantly (p < 0.05). In relation to the low weight classification according to the body mass index (BMI), it was observed that the anthropometric parameters such as corrected arm muscle area (R = 0.74, p < 0.001), adductor pollicis muscle thickness (R = 0.23, p = 0.046) and calf circumference (R = 0.81, p < 0.001) decreased as did biochemical parameters albumin (R = 0.26; p = 0.048) and capillary blood glucose (R = 0.34, p = 0.018).

Conclusion: anemia has an important relation with anthropometric markers that evaluate the depletion of lean mass; the BMI has a strong association with all the anthropometric parameters evaluated, as well as the albumin and capillary blood glucose, except with the values of hemoglobin.

MeSH terms

  • Adult
  • Aged
  • Anemia / complications*
  • Anemia / etiology*
  • Anthropometry
  • Body Mass Index
  • C-Reactive Protein / analysis
  • Cross-Sectional Studies
  • Enteral Nutrition / adverse effects*
  • Female
  • Humans
  • Inpatients
  • Male
  • Malnutrition / complications*
  • Malnutrition / etiology*
  • Middle Aged
  • Nutrition Assessment
  • Prospective Studies

Substances

  • C-Reactive Protein