Global epidemiology of viral hepatitis and national needs for complete control

Expert Rev Anti Infect Ther. 2018 Aug;16(8):625-639. doi: 10.1080/14787210.2018.1505503. Epub 2018 Aug 2.

Abstract

The World Health Organization recognizes that viral hepatitis is not only a massive public health issue but also a huge opportunity to improve quality of life and equity at a global level. Viral hepatitis causes about 1.5 million deaths each year and significantly affects the quality of life of hundreds of millions of people. To date, frail individuals in high-income countries and people living in low-income settings are paying the heaviest tool. Areas covered. Here we present a broad discussion on current knowledge and topical issues about the hepatitis pandemic. The report includes a structured overview of global epidemiology, including the definition of specific local epidemic profiles for each hepatitis agents (HAV, HBV, HCV, and HEV), and a perspective about the critical actions needed for achieving a complete control. Expert commentary. The control of viral hepatitis is currently, ethically urgent and even economically convenient. There is a wide consensus that viral hepatitis can be controlled through comprehensive intervention tailored on local needs addressing the issue of viral hepatitis as a unique public health issue. These strategies should include: (1) primary prevention (including vaccination and improved infection control), (2) improving diagnosis rate, and (3) management of existing cases of infections.

Keywords: Viral hepatitis; disease control; epidemic control; epidemiology; infection elimination; infection eradication.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiviral Agents / administration & dosage*
  • Developed Countries
  • Developing Countries
  • Global Health*
  • Hepatitis, Viral, Human / epidemiology*
  • Hepatitis, Viral, Human / virology
  • Humans
  • Public Health
  • Quality of Life
  • World Health Organization

Substances

  • Antiviral Agents